Subdivision
| • | 202. Cellular and Developmental Biology | [X] |
| | 1 | Name: | Dr. David D. Sabatini | | | Institution: | New York University School of Medicine | | | Year Elected: | 2000 | | | Class: | 2. Biological Sciences | | | Subdivision: | 202. Cellular and Developmental Biology | | | Residency: | Resident | | | Living? : |
Living
| | | Birth Date: | 1931 | | | | | | |
David D. Sabatini was born in Argentina, where he earned his medical degree from the Universidad Nacional del Litoral in 1954. Obtaining a Rockefeller Foundation Fellowship in 1960, Dr. Sabatini undertook postdoctoral training first at the Yale University School of Medicine and later at Rockefeller University. While at Yale, he introduced the glutaraldehyde fixation procedure for the preservation of subcellular structures, which revolutionized the field of biological electron microscopy by permitting cytochemical studies at the electron microscope level. In 1966, he received his Ph.D. from Rockefeller, where he remained as a faculty member in the Laboratory of Cell Biology. In 1972, Dr. Sabatini became Professor and Chairman of the Department of Cell Biology at the New York University School of Medicine, where he continued to investigate protein trafficking mechanisms, extending his work from the functions of the endoplasmic reticulum to the role of the Golgi apparatus in organelle and plasma membrane biogenesis. At New York University, he and his associates developed a system of cultured polarized kidney-derived epithelial cells (MDCK) which now serves as a common paradigm for studying the physiological properties of transporting epithelia. Using this system, they also discovered the polarized budding of enveloped viruses from epithelial cells. These studies provided the preeminent model currently used to investigate membrane protein sorting and plasma membrane biogenesis in epithelial cells. His current scientific interests continue to lie in the areas of protein traffic and membrane organelle biogenesis. David Sabatini has written more than 120 scientific publications and is the recipient of several scientific and teaching awards, including the Mayor's Award for Excellence in Science and Technology (2000) and New York University's Alpha Omega Alpha Robert J. Glaser Distinguished Teacher Award (2000). In 2014 he won the NAS Award in Molecular Biology. He became Frederick L. Ehrman Professor Emeritus of Cell Biology at New York University School of Medicine in 2016. Dr. Sabatini was elected to the American Philosophical Society in 2000. | |
| 2 | Name: | Dr. Shirley M. Tilghman | | | Institution: | Princeton University | | | Year Elected: | 2000 | | | Class: | 2. Biological Sciences | | | Subdivision: | 202. Cellular and Developmental Biology | | | Residency: | Resident | | | Living? : |
Living
| | | Birth Date: | 1946 | | | | | | |
Shirley M. Tilghman was elected Princeton University's 19th president on May 5, 2001, and assumed office on June 15, 2001. She became President Emerita in 2013. An exceptional teacher and a world-renowned scholar and leader in the field of molecular biology, she served on the Princeton faculty for 15 years before being named president. She continues now as Professor of Molecular Biology and Public Affairs. A native of Canada, Dr. Tilghman received her Honors B.Sc. in chemistry from Queen's University in Kingston, Ontario in 1968. After two years of secondary school teaching in Sierra Leone, West Africa, she obtained her Ph.D. in biochemistry from Temple University in Philadelphia. During postdoctoral studies at the National Institutes of Health, she made a number of groundbreaking discoveries while participating in cloning the first mammalian gene, and she continued to make scientific breakthroughs as an independent investigator at the Institute for Cancer Research in Philadelphia and as an adjunct associate professor of human genetics and biochemistry and biophysics at the University of Pennsylvania. Dr. Tilghman came to Princeton in 1986 as the Howard A. Prior Professor of the Life Sciences. Two years later, she also joined the Howard Hughes Medical Institute as an investigator. In 1998, she took on additional responsibilities as the founding director of Princeton's multi-disciplinary Lewis-Sigler Institute for Integrative Genomics. A member of the National Research Council's committee that set the blueprint for the U.S. effort in the Human Genome Project, Dr. Tilghman also was one of the founding members of the National Advisory Council of the Human Genome Project Initiative for the National Institutes of Health. She is renowned not only for her pioneering research but for her national leadership on behalf of women in science and for promoting efforts to make the early careers of young scientists as meaningful and productive as possible. Dr. Tilghman is a member of the National Academy of Sciences, the Institute of Medicine and the Royal Society of London. Her awards include a Lifetime Achievement Award from the Society for Developmental Biology, the Genetics Society of America Medal, and the L'Oreal-UNESCO Award for Women in Science. In 2014 she was named an Officer of the Order of Canada. She serves as a trustee of the Jackson Laboratory and the Carnegie Endowment for International Peace; as a director of Google, Inc.; and, beginning in October 2008, as chair of the Association of American Universities. In 2008 she was named to the board of trustees of the King Abdullah University of Science and Technology in Saudi Arabia. She was elected a member of the American Philosophical Society in 2000. | |
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